Category Archives: Uncategorized

Epithelioid Trophoblastic Tumor and Differential Diagnoses

A 47-year-old woman with prolonged uterine bleeding and initial endometrial sampling with proliferative endometrium.  Because of her prolonged uterine bleeding and leiomyomatous uterus she was taken to the operating room and hysterectomy was performed. Grossly, the uterus revealed multiple leiomyomas, but also a white-tan lesion in the lower uterine segment. Microscopic examination: the lesion revealed nodular, expansile growth. The nodules were composed of epithelioid cells with abundant eosinophilic cytoplasm, frequent mitotic figures, and the backgroundContinue reading “Epithelioid Trophoblastic Tumor and Differential Diagnoses”

Products of Conception

FIRST SEMESTER PRODUCTS OF CONCEPTION: Grossly small amount of tissue (tissue minus blood <4 -5cm). Villi are small (size of 2-2.5 endometrial glands or <4 mm) (figure 1). Trophoblastic proliferation in polarized (trophoblasts grow in columns towards the oxygen source) Exceptions: extrauterine (fallopian tube pregnancy) can show significant trophoblastic proliferation. This can be attributed toContinue reading “Products of Conception”